Job Description

Research Associate (RA & SRA)

South San Francisco, CA (Open to flex hours dependent on location)

6-Month Initial Contract (Strong Potential for Extension or FTE Conversion)

This role focuses on biochemical and biophysical assay development, protein characterization, and data analysis in a drug discovery setting. The ideal candidate will have hands-on experience with techniques like SPR, TR-FRET, FP, and LC/MS for protein characterization, along with expertise in analyzing large datasets using Genedata Screener or Expressionist. Preferred qualifications include experience with cell-based assays, automation, molecular glue mechanisms, and coding for data analysis. Industry experience is preferred, though strong academic candidates may be considered for lower-level roles.

Key Qualifications (Non-Negotiables):

• Biochemical & Biophysical Assays: Practical experience with SPR, TR-FRET, FP, BLI, ITC, nanoDSF, MSD, etc. (Industry experience preferred; if strictly academic, expect a lower-level placement.)
• Protein Characterization: Proficiency in LC/MS-based protein characterization techniques.
• Data Analysis & Visualization: Understanding of dry lab workflows and experience with Genedata Screener and/or Expressionist for handling large datasets.

Nice to Have:

• Cell-Based Assay Development: Hands-on experience with NanoBRET, CTG, AlphaLISA, or similar techniques.
• Drug Discovery Exposure: Familiarity with hit identification, validation, and screening platforms.
• Molecular Glues Knowledge: Any experience or baseline understanding of molecular glue mechanisms.
• Automation & Liquid Handling: Experience with SPT Dragonfly, Mosquito, Echo, Hamilton, etc. (Typically found in startups and smaller biotech companies.)
• Coding for Data Analysis: Experience with Python, R, or other scripting languages to support assay and screening workflows.

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